Integrins are transmembrane receptors that facilitate cell-extracellular matrix (ECM) adhesion.

Integrin alphavbeta3 extracellular domeens
PDB 1jv2 EBI.jpg
Structur o the extracellular segment o integrin alpha Vbeta3.[1]
Identifiers
SeembolIntegrin_alphaVbeta3
PfamPF08441
Pfam clanCL0159
InterProIPR013649
SCOP1jv2
SUPERFAMILY1jv2
OPM superfamily176
OPM protein2knc
Integrin alpha cytoplasmic region
PDB 1dpk EBI.jpg
Structure of chaperone protein PAPD.[2]
Identifiers
SeembolIntegrin_alpha
PfamPF00357
InterProIPR000413
PROSITEPDOC00215
SCOP1dpk
SUPERFAMILY1dpk
Integrin, beta cheen
Integrinalpha.png
Identifiers
SeembolIntegrin_beta
PfamPF00362
InterProIPR002369
SMARTSM00187
PROSITEPDOC00216
SCOP1jv2
SUPERFAMILY1jv2
Integrin beta 7 cytoplasmic domain: complex with filamin
PDB 2brq EBI.jpg
creestal structur o the filamin a repeat 21 complexed wi the integrin beta7 cytoplasmic tail peptide
Identifiers
SeembolIntegrin_b_cyt
PfamPF08725
InterProIPR014836
SCOP1m8O
SUPERFAMILY1m8O

ReferencesEedit

  1. Xiong JP, Stehle T, Diefenbach B, Zhang R, Dunker R, Scott DL, Joachimiak A, Goodman SL, Arnaout MA (October 2001). "Crystal structure of the extracellular segment of integrin alpha Vbeta3". Science. 294 (5541): 339–45. doi:10.1126/science.1064535. PMC 2885948. PMID 11546839.
  2. Sauer FG, Fütterer K, Pinkner JS, Dodson KW, Hultgren SJ, Waksman G (August 1999). "Structural basis of chaperone function and pilus biogenesis". Science. 285 (5430): 1058–61. doi:10.1126/science.285.5430.1058. PMID 10446050.