Betacoronavirus


Template:Coronavirus Betacoronaviruses (β-CoVs or Beta-CoVs) are ane o fower genera (Alpha-, Beta-, Gamma-, an Delta-) o coronaviruses. It is in the subfaimily Orthocoronavirinae in the faimily Coronaviridae, o the order Nidovirales. They are envelopit, positive-sense, single-straundit RNA viruses o zoonotic origin. The coronavirus genera are each componit o varyin viral lineages wi the betacoronavirus genus conteenin fower such lineages: A, B, C, D. In aulder leeteratur, this genus is kent as group 2 coronaviruses an aw.

Betacoronavirus
MERS-CoV pairticles as seen bi negative stain electron microscopy. Virions conteen chairacteristic club-like projections emanatin frae the viral membrane.
MERS-CoV pairticles as seen bi negative stain electron microscopy. Virions conteen characteristic club-like projections emanatin frae the viral membrane.
SARS-CoV-2 without background.png
Illustration of a SARS-CoV-2 virion
Virus classification e
(unranked): Virus
Realm: Riboviria
Phylum: incertae sedis
Order: Nidovirales
Faimily: Coronaviridae
Subfaimily: Orthocoronavirinae
Genus: Betacoronavirus
Subgenera an species

The Beta-CoVs o the greatest clinical importance concernin humans are OC43 (which can cause the common caud) an HKU1 o the A lineage, SARS-CoV an SARS-CoV-2 (which causes the disease COVID-19) o the B lineage,[3] an MERS-CoV o the C lineage. MERS-CoV is the first betacoronavirus belangin tae lineage C that is kent tae infect humans.[4][5]

The Alphacoronavirus an Betacoronavirus genera strynd frae the bat gene puil.[6][7][8]

ReferencesEedit

  1. "Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV) (in Inglis). October 2018. Retrieved 13 January 2019.
  2. Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). "Coronavirus Genomics and Bioinformatics Analysis". Viruses. 2 (8): 1804–20. doi:10.3390/v2081803. PMC 3185738. PMID 21994708. Figure 2. Phylogenetic analysis of RNA-dependent RNA polymerases (Pol) kharghar is the best of coronaviruses with complete genome sequences available. The tree was constructed by the neighbor-joining method and rooted using Breda virus polyprotein.
  3. "Phylogeny of SARS-like betacoronaviruses". nextstrain. Retrieved 18 January 2020.
  4. ProMED. MERS-CoV–Eastern Mediterranean (06) (http://www.promedmail.org/)
  5. Memish, Z. A.; Zumla, A. I.; Al-Hakeem, R. F.; Al-Rabeeah, A. A.; Stephens, G. M. (2013). "Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections". New England Journal of Medicine. 368 (26): 2487–94. doi:10.1056/NEJMoa1303729. PMID 23718156.
  6. Woo, P. C.; Wang, M.; Lau, S. K.; Xu, H.; Poon, R. W.; Guo, R.; Wong, B. H.; Gao, K.; Tsoi, H. W.; Huang, Y.; Li, K. S.; Lam, C. S.; Chan, K. H.; Zheng, B. J.; Yuen, K. Y. (2007). "Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features". Journal of Virology. 81 (4): 1574–85. doi:10.1128/JVI.02182-06. PMC 1797546. PMID 17121802.
  7. Lau, S. K.; Woo, P. C.; Yip, C. C.; Fan, R. Y.; Huang, Y.; Wang, M.; Guo, R.; Lam, C. S.; Tsang, A. K.; Lai, K. K.; Chan, K. H.; Che, X. Y.; Zheng, B. J.; Yuen, K. Y. (2012). "Isolation and characterization of a novel Betacoronavirus subgroup A coronavirus, rabbit coronavirus HKU14, from domestic rabbits". Journal of Virology. 86 (10): 5481–96. doi:10.1128/JVI.06927-11. PMC 3347282. PMID 22398294.
  8. Lau, S. K.; Poon, R. W.; Wong, B. H.; Wang, M.; Huang, Y.; Xu, H.; Guo, R.; Li, K. S.; Gao, K.; Chan, K. H.; Zheng, B. J.; Woo, P. C.; Yuen, K. Y. (2010). "Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup". Journal of Virology. 84 (21): 11385–94. doi:10.1128/JVI.01121-10. PMC 2953156. PMID 20702646.

Freemit airtinsEedit

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