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African trypanosomiasis, an aa kent as sleepin sickness, is an insect-borne parasitic disease o humans an ither ainimals.[1] It is caused bi protozoa o the speshies Trypanosoma brucei.[1] Thare are twa teeps that infect humans, Trypanosoma brucei gambiense (TbG) an Trypanosoma brucei rhodesiense (TbR).[1] TbG causes ower 98% o reportit cases.[1] Bauth are uisually transmittit bi the bite o an infectit tsetse flee an are maist common in rural auries.[1]

African trypanosomiasis
SynonymsAfrican sleepin sickness
Trypanosoma sp. PHIL 613 lores.jpg
Trypanosoma forms in a bluid smear
SpecialtyInfectious disease
SymptomsStage 1: Fivers, heidaches, itchiness, jynt pynes[1]
Stage 2: Tribble sleepin, confusion, puir coordination[2][1]
Uisual onset1–3 weeks post exposur[2]
CausesTrypanosoma brucei spread bi tsetse flees[1]
Diagnostic methodBluid smear, lumbar punctur[2]
MedicationPentamidine, suramin, eflornithine[1]
PrognosisFatal withoot treatment[1]
Frequency11,000[3]
Daiths3,500[4]

ReferencesEedit

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 WHO Media centre (March 2014). "Fact sheet N°259: Trypanosomiasis, Human African (sleeping sickness)". World Health Organization. Archived frae the oreeginal on 26 April 2014. Retrieved 25 April 2014. 
  2. 2.0 2.1 2.2 Kennedy, PG (Feb 2013). "Clinical features, diagnosis and treatment of human African trypanosomiasis (sleeping sickness)". Lancet Neurology. 12 (2): 186–94. doi:10.1016/S1474-4422(12)70296-X. PMID 23260189. 
  3. GBD 2015 Disease and Injury Incidence and Prevalence, Collaborators. (8 October 2016). "Global, regional, and national incidence, prevalence and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1545–1602. doi:10.1016/S0140-6736(16)31678-6. PMC 5055577 . PMID 27733282. 
  4. GBD 2015 Mortality and Causes of Death, Collaborators. (8 October 2016). "Global, regional, and national life expectancy, all-cause mortality and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015". Lancet. 388 (10053): 1459–1544. doi:10.1016/s0140-6736(16)31012-1. PMC 5388903 . PMID 27733281.